Regenerative Hyaluronic Acid Platform

LongevHA™ Regenerative Hyaluronic Acid Powered by Cellular Longevity

An advanced skin bio-revitalization platform that bridges structural hydration with cellular longevity signaling - combining dual-molecular-weight HA with NAD+, resveratrol, and mannitol.

Immediate hydrationCellular activationOxidative protection
LongevHA molecular structure
This is not simply a hydrating solution - it is a biologically intelligent formulation designed to optimize extracellular matrix (ECM) quality, oxidative balance, and cellular metabolic performance.
The Science Behind the Formula

Four synergistic actives. One regenerative system.

Every component is selected for a defined structural and regenerative role - working together to deliver immediate dermal support while activating long-term cellular longevity pathways.

01Dual-Weight Hyaluronic Acid

High + Low Molecular Weight HA

High Molecular Weight HA

  • Provides immediate volumetric hydration
  • Enhances barrier function
  • Creates structural dermal scaffolding

Low Molecular Weight HA

  • Improves dermal penetration
  • Stimulates fibroblast activity
  • Enhances collagen synthesis signaling
Clinical Advantage:
The dual-weight system delivers both instant hydration and biostimulatory activation, supporting improved skin elasticity, turgor, and texture.
Skin penetration diagram
NAD molecule
Mitochondria graphic
02Cellular Energy & Longevity

NAD+ - The Longevity Cofactor

Nicotinamide adenine dinucleotide (NAD+) is a critical cofactor in mitochondrial energy production and sirtuin activation.

Enhanced cellular repair pathways
Improved oxidative stress resistance
Support of fibroblast metabolic function
Promotion of dermal vitality
Clinical Relevance:
By supporting mitochondrial efficiency, NAD+ helps counteract the cellular energy decline associated with intrinsic and photo-aging.
03Potent Polyphenol Antioxidant

Resveratrol - Sirtuin Activation

Resveratrol is a well-studied polyphenol known for activating sirtuin pathways and protecting against oxidative stress.

Neutralization of reactive oxygen species (ROS)
Reduction of inflammatory signaling
Support of collagen preservation
Synergistic interaction with NAD+
Strategic Role:
Resveratrol enhances the longevity-focused approach by protecting dermal cells from environmental and metabolic stressors.
Resveratrol molecule
Antioxidant protection
Mannitol molecule
04Free Radical Protection

Mannitol - The Protective Stabilizer

Mannitol acts as a free radical scavenger and HA stabilizer, preserving formulation integrity and supporting dermal activity.

Protects HA from premature degradation
Reduces oxidative breakdown
Enhances formulation stability
Prolongs dermal activity
Why LongevHA™ Is Different

Structural support meets regenerative intelligence.

ComponentStructural BenefitRegenerative Benefit
Dual HAHydration + ECM supportFibroblast stimulation
NAD+-Cellular energy optimization
Resveratrol-Sirtuin activation + antioxidant
MannitolHA protectionOxidative stability
Skin layers
Clinical Indications

Engineered for regenerative-focused protocols.

LongevHA™ is ideal for practitioners prioritizing both prevention and correction.

Early to moderate dermal aging
Dull or fatigued skin
Loss of elasticity
Preventative longevity-based protocols
Combination with microneedling, electroporation, or energy-based devices
The EvoSkin Philosophy

Modern aesthetic medicine must move beyond correction toward regeneration.

LongevHA™ reflects this philosophy in every formulation and clinical use case.

Bio-compatible
Regenerative-oriented
Designed for synergy with advanced protocols
Aligned with cellular longevity science
In Summary

A next-generation HA platform for regenerative outcomes.

For practitioners who prioritize biologically intelligent skin therapy.

Immediate hydration
Improved elasticity
Fibroblast metabolism
Oxidative protection
Longevity revitalization

Elevate your patients to their best with LongevHA™

Connect with our clinical team to bring biologically intelligent, longevity-focused skin revitalization to your practice.